Category: Repository

Author : Wahjusaputri, Sintha Abstrak: Download disini !  

Landasan Ilmu Pendidikan Author : Yoce Aliah Darma, Yoce Abstrak: Download disini !  

Author : Abstrak: Download disini !  

Author : Abstrak: Download disini !  

6-Mercaptopurine is a chemotherapeutic agent of the antimetabolite class. This study aims to analyze
simultaneous validation of 6-mercaptopurine (6-MP), 6-methylmercaptopurine (6-MMP), and 6-thioguanosine-5’-
monophosphate (6-TGMP) in dried blood spot (DBS) using ultra performance liquid chromatography-tandem mass
spectrometry (UPLC-MS/MS). An accurate volume of 60 μL blood was spotted onto DBS-CAMAG paper and then
extracted using methanol 90% (v/v) containing an internal standard of 5-fluorouracil (5-FU). Separation was
performed using a Waters Acquity UPLC BEH AMIDA column 1.7 μm (2.1 x 100 mm) with a mobile phase mixture of
0.2% (v/v) formic acid in water−0.1% (v/v) formic acid in acetonitrile-methanol with gradient elution and flow rate of
0.2 mL/min. Mass detection was done using Waters Xevo TQD with positive electrospray ionization (ESI) for 6-MP,
6-MMP, 6-TGMP and negative ESI for 5-FU, in multiple reaction monitoring mode. Detection rates of 6-MP, 6-MMP,
6-TGMP and 5-FU were m/z 153.09 > 119.09; 167.17 > 126.03; 380.16 > 168.00); 129.09 > 42.05, respectively. This
method is linear across the range of 25.5–1020 ng/mL for 6-MP, 6-MMP and 6-TGMP. This method is valid for the in
vitro simultaneous analysis of 6-MP, 6-MMP and 6-TGMP in DBS, based on European Medicine Agency guidelines.

Author : Muhammad, Nurrasyidin Abstrak: Download disini !  

This article discusses on sector-specific and spatial-specific multipliers in Indonesian economy using
6-country-30 sector input-output tables for the year 2000, 2005, 2010 and 2014. The results show that
firstly, in all years, there were 20 sectors with total output multipliers more than 2. Flow-on effects
were higher than initial effects. These sectors should be prioritized if increasing of total output is the
objective of Indonesian economic development as total output will be created with less initial efforts.
Secondly, in the year of 2000, average percentage of multipliers occurred in own-sector was 56.23
per cent, and increase slightly in 2005 (57.38%) and 2010 (58.93%), but decrease in 2014 (57.98%).
Correlation between total output multipliers and percentage of multipliers occurred in other-sector
was positive, very strong and statistically significant. The higher total output multipliers, the higher
percentage of multipliers occurred in other-sector. Thirdly, in the year of 2000, average percentage
of multipliers occurred in other-countries was 21.34 per cent and decrease slightly in 2005 (20.22%)
and 2010 (18.14%), but increase in 2014 (20.55%). Correlation between total output multipliers and
percentage of multipliers occurred in other-countries were positive, very strong and statistically
significant. The higher total output multipliers, the higher multipliers occurred in other-countries.

Author : Abstrak: Download disini !  

Jaminan Kesehatan Nasional or JKN realized as the one of problem-solving for equity of healthcare in Indonesian setting. At the same point, it has to compatible with all aspects in health financing issues by its newly adopted systems. This review aims to reveal JKN health financing policy since it implemented by 2014 in Indonesia. Several
bibliographies databases were identified to conduct literature reviews that comprised of international and national/local journals. It founds that JKN principles focuses on mutual support, not-for-profit, good governance, and portability aspects. JKN enrollment consisted of two types polisholders including incapable polis insurance (PBI JKN) that bear by the Indonesian government, and capable polis insurance (none PBI JKN). JKN have to synergize with recent existing challenges including integration from previous regional health insurance (Jamkesda), healthcare facilities, package benefit, financing issue as well as the deficit issue which happened as lower dues that making by JKN polisholder than the high claim by the healthcare facilities particularly in hospitals. Although, JKN emerges to tackle the inequity of healthcare in all Indonesian regions, the existing settled Jamkesda in several regions, particularly regions with high regional income, made JKN integration as the setback health financing on its regions. Limited healthcare facilities that cooperated with BPJS-Kesehatan also challenged the JKN implementation as well as financial lose in affecting by mismatch between medical expenditures with JKN claimed as per package. It concludes that the political willing to choose several options including to prevent JKN deficit depend on the leader commitment to make JKN as not for another journey but it shall be the destination for health financing in Indonesia.

Author : Abstrak: Download disini !