Author : Abstrak: Download disini !
Category: Repository
Untitled
Author : Srifiana, Yudi Abstrak: Download disini !
Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form
Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum corneum so as to increase the bioavailability of curcumin. This study aimed to obtain the ratio between curcumin with dendrimer of PAMAM G4: PEG in the formation of curcumin dendrimer combined in the base of carbomer 940 to produce the optimal of physical characteristics of dendrimer and physical stability of gel. The study was conducted by conjugating PAMAM G4 with PEG with a ratio of 1:5, and then encapsulated curcumin in dendrimer with a ratio of 1:0.2 (F1); 1:0.02 (F2) and 1:0.002 (F3). Further dendrimers that have encapsulated curcumin were formulated in a gel with a carbopol base 940. The physical characteristics of the gel tested were polydispersity index, zeta potential and particle size, organoleptic, flow properties, and pH at weeks 0, 2, 4 and 6. The results shows that F1 has zeta potential highest and the lowest viscosity of the other formula, while F3 has the lowest potential zeta and highest viscosity of other formulas. In addition, the polydispersity index, particle size, organoleptic, flow properties and pH; there are not a significant difference in each formula, but the particle size, zeta potential, and viscosity of gel can decrease with longer storage time. Conclusion of this study that the ratio between curcumin and dendrimer PAMAM G4:PEG of 1: 0.2 shows the optimal of physical characteristics of dendrimer and physical stability of gel.
Untitled
Author : Marliyati, Sri Anna Abstrak: Download disini !
Untitled
Author : Abstrak: Download disini !
Untitled
Author : Abstrak: Download disini !
ANALISIS ASUPAN ZAT GIZI MAKRO DAN INSIDEN PENYAKIT JANTUNG KORONER PADA PENDUDUK USIA 25-44 TAHUN DI BOGOR (STUDIKOHOR PTM BALITBANGKES 2011-2014)
Lia Nur Uyun
Fakultas Ilmu-Ilmu Kesehatan Universitas Muhammadiyah Prof. Dr. Hamka
Leni Sri Rahayu
Coronary heart disease (CHD) is the number one cause of death from non-communicable diseases(NCD), both in Indonesia and in the world. CHD has several risk factors, including food intakewhich is not good. This study was to analyze the food intake on the incidence of CHD in menand women aged 25-44 years in Bogor. This study was a prospective cohort study using a cohortstudy data NCD of Agency for Health Research and Development Ministry of Health of theRepublic of Indonesia. Sampling with purposive sampling technique. Analysis of the data in thisstudy is the univariate analysis. Number of respondents were 1587 subjects. The study foundthe incidence of CHD of 1,20%, the incidence of CHD in men of 1,14% and more affected byCHD are women (1,22%). Most of CHD patients aged 40-44 years old. Protein intake of men15,4% and fat intake of women 31,1%.
Untitled
Author : Uyun, Lia Nur Abstrak: Download disini !
Untitled
Author : Abstrak: Download disini !
PEMANFAATAN TEPUNG TEMPE DALAM PEMBUATAN COOKIES KAYA PROTEIN DAN SERAT
Decreasing in protein consumption and low consumption of fber was one of the nutritionalproblems in the community, especially in young adults. One of solutions to solve its problem,namely by making food products with a source of protein and fber derived food ingredients suchas flour. The purpose of this study was to examine the use of tempeh flour as a substitutematerial in the production of cookies as a food product with a source of protein and fber. Theamount was, i.e. 70%, 80% and 90% of tempeh flour that had substituted to wheat flour.Organoleptic test with semi-trained panelists had done to elect the best cookies formula. This studyused complete randomized experimental design (CRD) with one factor and two replications. Theresults of this study is higher substitution of tempeh flour to wheat flour would produce lowerquality of color, texture, flavor and aroma of cookies and lower panelist preference level of color,texture, flavor and aroma of cookies. Based on the hedonic product quality assessment,the elected cookies with 70% substitution of tempeh flour has brown color, slightly crunchytexture, slightly sweet taste and dominant of tempeh aroma. The elected cookies product in100 grams contains 506,8 kcal of energy, 37,2 grams of carbohydrtares, 23,35 grams of protein,29,4 grams of fat and 9,98 grams of dietary fiber.